That’s impressive that your younger brother chose to take on such a feat. Its commendable for anyone who tries to play the guitar in a harder way to take on more of a challenge than it already is! Thanks for the response and input!
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Hi Zach!
Maybe a bit off-topic here as I don’t really have additional info to add since you’ve gotten a bunch of advice above…
Have you watched any of Nitsuj’s (Justin backwards) videos? At the least, you can watch Justin do practice routines while trying to learn left-handed… all the orientation (guitar, strumming hand & fretting hand) is correct for a left-handed player… just a little FYI in case you didn’t know about Nitsuj! 
Tod